If you really want to validate your intuition that we human beings don't know "shit from Shinola" about the universe, well, just spend some time with the folks who study and theorize about it for a living.
For instance, take a gander at this little essay that made the NY Times Science section by Dennis Overbye.
If I'm reading this thing correctly, the universe is actually rippling backward in time (!?) to sabotage the Large Hadron Collider in Geneva. Why would the universe do this? Because the Higgs boson (no, this is not a type of Buffalo), which the collider is designed to unleash, is so horrific to the future of everything, that it must be killed in it's cradle.
So the theory says that the Large Hadron Collider will never work. It will always and forever be sabotaged by universal forces looking out for it's own self preservation.
Got that? The universe is conspiring against us so we don't completely, totally fuck things up. Physics has to be the ultimate trip, eh?
So, as the Bhagavad Gita told us many years ago - everything we see is Maya - Illusion. Or as William Blake once wrote: "If the doors of perception were cleansed every thing would appear to man as it is, infinite. For man has closed himself up, till he sees all things through narrow chinks of his cavern."
The trouble is taking massive doses of LSD or mescaline won't really open up those narrow chinks for long.
No, maybe the real "tragedy" of our existence is to be able to imagine the universe as it really is, but never be able to actually perceive it.
All come on and no come. And behind the scenes, under the cover of the great clouds of unknowing the real shit happens!